Molecular Mechanics Studies of Antihypertensive Val-Tyr Dipeptide

Akverdieva G. A., Godjayev N. M., AKYÜZ S., Akyuz T., Dogan N. E.

ASIAN JOURNAL OF CHEMISTRY, cilt.22, sa.1, ss.311-318, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 1
  • Basım Tarihi: 2010
  • Dergi Adı: ASIAN JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.311-318
  • İstanbul Kültür Üniversitesi Adresli: Evet

Özet

The spatial structure of anti hypertensive dipeptide,Valine-Tyrosine was investigated within molecular mechanics framework. It ha, been shown that the molecule has such a structural organization which does not exclude the realization of two types of conformation: folded and extended. The energy and geometrical parameters for the optimal conformations of dipeptide are obtained. The electronic characteristics for these structures were analyzed by quantum chemical calculations.